USB Interface IC – Mouser Guatemala

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MCP2221 USB-to-UART/I²C Converter

Microchip Technology MCP2221 USB-to-UART/I²C Converter supports full-speed USB at 12Mb/s and enables USB connectivity in applications with UART and I²C interfaces. The MCP2221 converter integrates USB termination resistors and the oscillator needed for USB operation. This converter comes with four GP pins that provide miscellaneous functionalities. These functionalities include GPIO, USBCFG, SSPND, Clock Output, ADC, DAC, interrupt detector.

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Part #

USB Interface IC USB to I2C Bridge Device

MCP2221-I/ST
Microchip Technology
1: $2.88
496In Stock

Mfr. Part #
MCP2221-I/ST

Mouser Part #
579-MCP2221-I/ST

Microchip Technology

USB Interface IC USB to I2C Bridge Device

Learn More

Datasheet

496In Stock

$2.88

$2.58

$2.16

Min.: 1
Mult.: 1

MCP2221

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

TSSOP-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB 2.0 to I2C Converter with GPIO

MCP2221A-I/ST
Microchip Technology
1: $2.80
8,309In Stock

Mfr. Part #
MCP2221A-I/ST

Mouser Part #
579-MCP2221A-I/ST

Microchip Technology

USB Interface IC USB 2.0 to I2C Converter with GPIO

Learn More

Datasheet

8,309In Stock

$2.80

$2.33

$2.13

Min.: 1
Mult.: 1

MCP2221A

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

TSSOP-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB 2.0 to I2C Converter with GPIO

MCP2221AT-I/ST
Microchip Technology
1: $2.80
9,091In Stock

Mfr. Part #
MCP2221AT-I/ST

Mouser Part #
579-MCP2221AT-I/ST

Microchip Technology

USB Interface IC USB 2.0 to I2C Converter with GPIO

Learn More

Datasheet

9,091In Stock

Cut Tape

$2.80

Reel

$2.80

MouseReel Available

Min.: 1
Mult.: 1

: 2,500

MCP2221A

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

TSSOP-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Reel, Cut Tape, MouseReel

USB Interface IC USB to I2C Bridge Device

MCP2221T-I/ST
Microchip Technology
1: $3.15
3,627In Stock

Mfr. Part #
MCP2221T-I/ST

Mouser Part #
579-MCP2221T-I/ST

Microchip Technology

USB Interface IC USB to I2C Bridge Device

Learn More

Datasheet

3,627In Stock

Cut Tape

$3.15

$2.62

$2.61

Reel

$2.61

$2.38

MouseReel Available

Min.: 1
Mult.: 1

: 2,500

MCP2221

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

TSSOP-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Reel, Cut Tape, MouseReel

USB Interface IC USB to I2C Bridge Device

MCP2221-I/ML
Microchip Technology
1: $3.15
1,708In Stock

Mfr. Part #
MCP2221-I/ML

Mouser Part #
579-MCP2221-I/ML

Microchip Technology

USB Interface IC USB to I2C Bridge Device

Learn More

Datasheet

1,708In Stock

$3.15

$2.62

$2.38

Min.: 1
Mult.: 1

MCP2221

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

QFN-16

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB to I2C Bridge Device

MCP2221-I/P
Microchip Technology
1: $3.55
533In Stock

Mfr. Part #
MCP2221-I/P

Mouser Part #
579-MCP2221-I/P

Microchip Technology

USB Interface IC USB to I2C Bridge Device

Learn More

Datasheet

533In Stock

$3.55

Min.: 1
Mult.: 1

MCP2221

USB Controllers

Bridge, USB to UART/I2C

Through Hole

PDIP-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB 2.0 to I2C/UART Protocol Converter with GPIO, AEC-Q100 Qualified

MCP2221A-I/ML
Microchip Technology
1: $2.80
4,211In Stock

Mfr. Part #
MCP2221A-I/ML

Mouser Part #
579-MCP2221A-I/ML

Microchip Technology

USB Interface IC USB 2.0 to I2C/UART Protocol Converter with GPIO, AEC-Q100 Qualified

Learn More

Datasheet

4,211In Stock

$2.80

$2.33

$2.13

Min.: 1
Mult.: 1

MCP2221A

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

QFN-16

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB 2.0 to I2C Converter with GPIO

MCP2221A-I/P
Microchip Technology
1: $3.20
846In Stock

Mfr. Part #
MCP2221A-I/P

Mouser Part #
579-MCP2221A-I/P

Microchip Technology

USB Interface IC USB 2.0 to I2C Converter with GPIO

Learn More

Datasheet

846In Stock

$3.20

$2.67

$2.42

Min.: 1
Mult.: 1

MCP2221A

USB Controllers

Bridge, USB to UART/I2C

Through Hole

PDIP-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB 2.0 to I2C Converter with GPIO

MCP2221A-I/SL
Microchip Technology
1: $2.53
3,055In Stock
4,047Expected 9/15/2026

Mfr. Part #
MCP2221A-I/SL

Mouser Part #
579-MCP2221A-I/SL

Microchip Technology

USB Interface IC USB 2.0 to I2C Converter with GPIO

Learn More

Datasheet

3,055In Stock

4,047Expected 9/15/2026

$2.53

$2.13

$1.93

Min.: 1
Mult.: 1

MCP2221A

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

SOIC-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB 2.0 to I2C Converter with GPIO

MCP2221AT-I/ML
Microchip Technology
1: $2.86
1,199In Stock
6,600Expected 10/26/2026

Mfr. Part #
MCP2221AT-I/ML

Mouser Part #
579-MCP2221AT-I/ML

Microchip Technology

USB Interface IC USB 2.0 to I2C Converter with GPIO

Learn More

Datasheet

1,199In Stock

6,600Expected 10/26/2026

Cut Tape

$2.86

$2.80

$2.60

$2.58

View

Reel

$2.13

MouseReel Available

Min.: 1
Mult.: 1

: 3,300

MCP2221A

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

QFN-16

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Reel, Cut Tape, MouseReel

USB Interface IC USB 2.0 to I2C Converter with GPIO

MCP2221AT-I/SL
Microchip Technology
1: $2.53
873In Stock
2,600Expected 9/2/2026

Mfr. Part #
MCP2221AT-I/SL

Mouser Part #
579-MCP2221AT-I/SL

Microchip Technology

USB Interface IC USB 2.0 to I2C Converter with GPIO

Learn More

Datasheet

873In Stock

2,600Expected 9/2/2026

Cut Tape

$2.53

$2.13

$2.12

Reel

$1.93

MouseReel Available

Min.: 1
Mult.: 1

: 2,600

MCP2221A

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

SOIC-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Reel, Cut Tape, MouseReel

USB Interface IC USB to I2C Bridge Device

MCP2221-I/SL
Microchip Technology
1: $2.89
308In Stock

Mfr. Part #
MCP2221-I/SL

Mouser Part #
579-MCP2221-I/SL

Microchip Technology

USB Interface IC USB to I2C Bridge Device

Learn More

Datasheet

308In Stock

$2.89

$2.41

$2.18

Min.: 1
Mult.: 1

MCP2221

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

SOIC-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Tube

USB Interface IC USB to I2C Bridge Device

MCP2221T-I/ML
Microchip Technology
3,300: $2.61
Non-Stocked Lead-Time 22 Weeks

Mfr. Part #
MCP2221T-I/ML

Mouser Part #
579-MCP2221T-I/ML

Microchip Technology

USB Interface IC USB to I2C Bridge Device

Learn More

Datasheet

Non-Stocked Lead-Time 22 Weeks

Reel

$2.61

Min.: 3,300
Mult.: 3,300

: 3,300

MCP2221

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

QFN-16

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Reel

USB Interface IC USB to I2C Bridge Device

MCP2221T-I/SL
Microchip Technology
2,600: $2.89
Non-Stocked Lead-Time 21 Weeks

Mfr. Part #
MCP2221T-I/SL

Mouser Part #
579-MCP2221T-I/SL

Microchip Technology

USB Interface IC USB to I2C Bridge Device

Learn More

Datasheet

Non-Stocked Lead-Time 21 Weeks

Reel

$2.89

Min.: 2,600
Mult.: 2,600

: 2,600

MCP2221

USB Controllers

Bridge, USB to UART/I2C

SMD/SMT

SOIC-14

USB 2.0

Full Speed (FS)

12 Mb/s

3 V

5.5 V

13 mA

- 40 C

+ 85 C

Reel

MCP2221 USB-to-UART/I²C Converter

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